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glossary:blood_thinner [2008/05/01 05:53]
Pat O'Connor created
glossary:blood_thinner [2012/10/16 14:40] (current)
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 +(1) Blood-thinner:​ A common name for an anticoagulant agent used to prevent the formation of [[blood clot]]s. Blood-thinners do not really thin the [[blood]]. They prevent it from clotting.
 +Blood-thinners (anticoagulants) have various uses. Some are used for the prophylaxis (prevention) of thromboembolic disorders; others are used for the treatment of thromboembolism. (Thrombi are clots. Emboli are clots that break free, travel through the [[bloodstream]],​ and lodge in a vessel) The anticoagulant drugs used for these clinical purposes include:
 +Intravenous heparin -- which acts by inactivating thrombin and several other clotting factors required for a clot to form; 
 +Oral anticoagulants such as warfarin and dicumarol -- which act by inhibiting the [[liver]]'​s production of vitamin K dependent factors crucial to clotting.
 +Anticoagulant solutions are also used for the preservation of stored whole blood and blood fractions. These anticoagulants include heparin and acid citrate dextrose (commonly called ACD).
 +Anticoagulants are also used to keep laboratory blood specimens from clotting. These agents include not only heparin but also several agents that make calcium ions unavailable to the clotting process and so prevent the formation of clots; these agents include ethylenediaminetetraacetic acid (commonly called EDTA), citrate, oxalate and fluoride.
 +(2) A blood thinner, also called an anti-coagulant,​ is used to stop [[platelets]],​ or heavy cells, present in [[blood plasma]] from forming clots. They are most used in those who are at risk for [[heart attack]], [[stroke]], or aneurisms. A blood thinner can be composed of several different chemical formations. The most common blood thinner, and most often used is aspirin, taken in doses of 81mg per day, essentially one baby aspirin.
glossary/blood_thinner.txt ยท Last modified: 2012/10/16 14:40 (external edit)