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glossary:megakaryocytes [2012/10/16 14:40] (current)
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|+||The largest cells seen in bone marrow aspiarates, and produce platelets by cytoplasmic fragmentation. |
|+||The precursor of of the megakaryocytes in [[bone marrow]] is the megaryoblast, which duplicates its nuclear and cytoplasmic constiuents up to seven times without [[cell]] division, each causing increased ploidy, nuclear lobulation and cell size.|
|+||cytoplasmic maturation involves the elaboration of granules, vesicles and demarcation membranes and progessive loss of free ribosomes and rough endoplasmic reticulum.|